Lijian Zhao

The paper creates a spatiotemporal transcriptome atlas of human embryos after gastrulation, revealing organ-specific regulons and regulatory networks during development.

This study identifies 13 novel genetic associations and confirms 17 existing ones between SNPs and neonatal metabolites using genome-wide association analysis of maternal low-pass genomes.

This study identifies 30 novel metabolite-gene associations in 34,394 Chinese pregnant women and finds pleiotropy and causal relationships between metabolites and diseases.

This paper introduces Genetic Transformer (GeneT), an LLM-driven method that significantly reduces candidate variant numbers and improves recall in rare disease diagnosis.

This study shows that adding genetic screening to newborn hearing tests in China improves detection and reduces loss-to-follow-up, with significant benefits for identifying preventable hearing loss.