Ya Ming Gao

The paper creates a spatiotemporal transcriptome atlas of human embryos after gastrulation, revealing organ-specific regulons and regulatory networks during development.

This study identifies 30 novel metabolite-gene associations in 34,394 Chinese pregnant women and finds pleiotropy and causal relationships between metabolites and diseases.

BDdb is a database integrating multi-omics data, cfDNA data, and biomarkers for birth defects, enabling data exploration and analysis for research and clinical applications.

This study creates the first single cell atlas of T21 cerebral cortex, identifying dysregulated genes and developing a platform for data exploration.

This study validates the use of exosomal DNA from maternal plasma for noninvasive prenatal detection of fetal trisomy and single gene disease.