Developmental BiologyNature CommunicationsPeer-reviewed
Polycomb Repressive-Deubiquitinase Complex Safeguards Oocyte Epigenome and Female Fertility by Restraining Polycomb Activity
Jinwen Kang, Peiyao Liu, Shoko Ichimura…·Zhiyuan Chen
This study identifies BAP1 as a key regulator of oocyte epigenome maintenance by restricting Polycomb activity, ensuring proper transcription and female fertility.