Author

Dipon Saha

University of British ColumbiaORCID 0009-0000-0885-2011Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Assay:proteomics· 1 Organism:virus· 1

Frequent Co-Authors

Dieter BrömmeiD· 2 shared Eliot Mar· 2 shared Filip Van PetegemiD· 2 shared S. Yasin Tabatabaei DakhiliiD· 2 shared Yu Seby CheniD· 2 shared Bryan J. FraseriD· 1 shared C.H. ArrowsmithiD· 1 shared Masahiro NiikuraiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

Dieter BrömmeORCID

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2 papers

Recent·Most cited

Functional Characterization of SARS-CoV-2 3CLpro Variants

Dipon Saha, S. Yasin Tabatabaei Dakhili, Eliot Mar, Yu Seby Chen, Filip Van Petegem, Dieter Brömme

This study examines how SARS-CoV-2 3CLpro variants maintain catalytic activity despite distant substitutions, revealing structural adaptations that preserve function.

bioRxiv · Sep 10, 2026 · PreprintBiochemistry

Cathepsin K as a Key Protease in Processing of SARS-CoV-2 Spike Activation Sites and a Target of Dual-Inhibition

S. Yasin Tabatabaei Dakhili, Dipon Saha, Preety Panwar, Eliot Mar, Olivier Hinse, Yu Seby Chen, Bryan J. Fraser, C.H. Arrowsmith, Masahiro Niikura, Filip Van Petegem, Dieter Brömme

This study identifies Cathepsin K as a key host protease for SARS-CoV-2 spike activation and shows it can be inhibited by existing drugs.

bioRxiv · Oct 3, 2025 · PreprintBiochemistry