Author

Preety Panwar

University of British ColumbiaORCID 0009-0002-0574-0318Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Dieter BrömmeiD· 4 shared Eliot Mar· 2 shared Olivier HinseiD· 2 shared S. Yasin Tabatabaei DakhiliiD· 2 shared A Martínez-MartíneziD· 1 shared Alex Bersellini FarinottiiD· 1 shared Azar Baharpoor· 1 shared Bryan J. FraseriD· 1 shared

Activity by Year

2021-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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4 shared papersBiochemistry

Dieter BrömmeORCID

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Author profile →

4 papers

Recent·Most cited

Cathepsin K as a Key Protease in Processing of SARS-CoV-2 Spike Activation Sites and a Target of Dual-Inhibition

S. Yasin Tabatabaei Dakhili, Dipon Saha, Preety Panwar, Eliot Mar, Olivier Hinse, Yu Seby Chen, Bryan J. Fraser, C.H. Arrowsmith, Masahiro Niikura, Filip Van Petegem, Dieter Brömme

This study identifies Cathepsin K as a key host protease for SARS-CoV-2 spike activation and shows it can be inhibited by existing drugs.

bioRxiv · Oct 3, 2025 · PreprintBiochemistry

Reverse Proteolysis Uncovers a Hidden Dimension of the Peptidome

S. Yasin Tabatabaei Dakhili, Preety Panwar, Olivier Hinse, Eliot Mar, Jason C. Rogalski, Leonard J. Foster, Dieter Brömme

This paper demonstrates that lysosomal cysteine cathepsins can generate fusion peptides through reverse proteolysis, revealing a new dimension of protease activity and peptide diversification.

bioRxiv · Sep 2, 2025 · PreprintBiochemistry

Cathepsin K inhibitors promote osteoclast-osteoblast communication and engagement of osteogenesis

Preety Panwar, Jacob Bastholm Olesen, Jean‐Marie Delaissé, Kent Søe, Dieter Brömme

This paper shows cathepsin K inhibitors enhance osteoclast-osteoblast communication and promote osteogenesis, suggesting their unique role in balancing bone resorption and formation.

JBMR Plus · Apr 29, 2025Peer-reviewedCell Biology

Bone innervation and vascularization regulated by osteoclasts contribute to refractive pain-related behavior in the collagen antibody-induced arthritis model

Resti Rudjito, Nilesh M. Agalave, Alex Bersellini Farinotti, Azar Baharpoor, A Martínez-Martínez, Enriqueta Muñoz‐Islas, Preety Panwar, Dieter Brömme, Julie Barbier, Fabien Marchand, Patrick Mehlen, Thomas Levin Andersen, Juan Miguel Jiménez‐Andrade, Camilla I. Svensson

This study shows osteoclasts contribute to pain in arthritis by affecting bone vascularization and innervation, and inhibitors can reverse this pain.

bioRxiv · Apr 19, 2021 · PreprintNeuroscience