S. Yasin Tabatabaei Dakhili

TransPepMS verifies peptides not in reference proteomes by resolving ambiguities in mass-spectrometry data to distinguish genuine non-canonical peptides from false positives.

This study identifies cathepsin K-generated spliced peptides as potential autoantigens in RA, compatible with HLA-DR4 presentation.

This study examines how SARS-CoV-2 3CLpro variants maintain catalytic activity despite distant substitutions, revealing structural adaptations that preserve function.

This study identifies Cathepsin K as a key host protease for SARS-CoV-2 spike activation and shows it can be inhibited by existing drugs.

This paper demonstrates that lysosomal cysteine cathepsins can generate fusion peptides through reverse proteolysis, revealing a new dimension of protease activity and peptide diversification.