Cecilia Fruet

This study identifies how the intestinal microbiota drives the evolution of pathoadaptive traits in ESBL E. coli through adhesion and biofilm formation.

The paper introduces ProteomeLM-HPI, a language model adapted to predict cross-species host-pathogen interactions using proteome context and fine-tuning.

The paper shows environment heterogeneity can amplify natural selection and speed up mutant fixation in graph-structured populations, depending on migration rates and mutant fitness advantages.

The paper shows spatial structure in bacterial populations increases the probability of evolutionary rescue by antibiotic resistance through enhanced fixation of resistant mutants in small subpopulations.

This paper presents a computational model of GfcD, an outer-membrane β-barrel protein, showing it facilitates lipid-anchored polysaccharide export through a lateral aperture.