Shu He

The paper introduces a blocking primer to improve detection of tick-borne pathogens in Ixodes scapularis ticks using 16S rRNA metabarcoding, achieving sensitivity comparable to qPCR and detecting additional pathogens.

This paper develops a non-human primate model of Alzheimer's disease by overexpressing human tau in the hippocampus, showing AD-like pathological features.

This study shows that enhancing NeuroD1 expression can convert astrocytes into neurons in mice, but lineage-traced astrocytes require stronger conversion signals.