Andrew P Pahnke

This study shows that Trsp is essential for T cell development and function, particularly regulatory T cells, and its deficiency leads to fatal autoimmunity.

This study shows that Mecr, a mitochondrial fatty acid synthesis gene, is critical for CD4+ T cell metabolism, function, and survival, with implications for inflammatory diseases and mitochondrial disorders.

This study shows that gut commensal bacteria can translocate to the brain in mice with dysbiosis and neurological disease, correlating with neuroinflammation and protein aggregation.