Author

Juan F. Marín

University of DelawareORCID 0009-0000-3134-6782Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Brittany A. Shimanski· 1 shared Jacek JemielityiD· 1 shared Jeffrey S. MugridgeiD· 1 shared Joanna KowalskaiD· 1 shared Jodi A. Hadden‐PerillaiD· 1 shared Kasun Dilshan Abeyrathne Eluwawalage· 1 shared Lucas O. Calzini· 1 shared Marcin WarmińskiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Brittany A. Shimanski

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1 paper

Recent·Most cited

BiochemistryJournal of Biological ChemistryPeer-reviewedSep 17, 2026

RNA demethylase FTO uses conserved aromatic residues to recognize the mRNA 5' cap and promote efficient m6Am demethylation

Brittany A. Shimanski, Juan F. Marín, Marcin Warmiński…·Jeffrey S. Mugridge

This study identifies conserved aromatic residues in FTO that recognize the mRNA 5' cap and enhance m6Am demethylation, providing structural insights into FTO's selectivity for m6Am over m6A.

DOI 10.1016/j.jbc.2026.113573

mechanistic / dynamical modelchromatin & epigenetic regulation

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