Jodi A. Hadden‐Perilla

This study identifies conserved aromatic residues in FTO that recognize the mRNA 5' cap and enhance m6Am demethylation, providing structural insights into FTO's selectivity for m6Am over m6A.

The paper develops and validates a method to quantify dynamic protein binding pockets using the HBV capsid assembly modulator site as a model, demonstrating robust performance across conformational states.

The paper uses a kinetic Monte Carlo model to simulate how CAMs alter HBV capsid assembly, revealing mechanisms that lead to noninfectious structures.

This study compares the binding of CAMs to two forms of HBV capsid protein, showing structural differences in CAM site adaptation between assembly-active and -inactive forms.

This paper uses all-atom MD simulations to show how CAMs alter HBV capsid structure by inducing strain propagation and morphological changes through interdimer interfaces.

This study uses molecular dynamics simulations to investigate how dye conjugation affects the biophysical properties of virus-like particles, revealing structural and electrostatic changes that influence superradiance.

The paper performs all-atom MD simulations of the HPV16 capsid to study its structure, dynamics, and potential for drug design and antibody engineering.