Author

Brittany A. Shimanski

University of Delaware

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:chromatin & epigenetic regulation· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Jacek JemielityiD· 2 shared Jeffrey S. MugridgeiD· 2 shared Joanna KowalskaiD· 2 shared Kasun Dilshan Abeyrathne Eluwawalage· 2 shared Marcin WarmińskiiD· 2 shared Jodi A. Hadden‐PerillaiD· 1 shared Juan F. MaríniD· 1 shared Lucas O. Calzini· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Jacek JemielityORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

RNA demethylase FTO uses conserved aromatic residues to recognize the mRNA 5' cap and promote efficient m6Am demethylation

Brittany A. Shimanski, Juan F. Marín, Marcin Warmiński, Kasun Dilshan Abeyrathne Eluwawalage, Lucas O. Calzini, Riley M McKeon, Joanna Kowalska, Jacek Jemielity, Jodi A. Hadden‐Perilla, Jeffrey S. Mugridge

This study identifies conserved aromatic residues in FTO that recognize the mRNA 5' cap and enhance m6Am demethylation, providing structural insights into FTO's selectivity for m6Am over m6A.

Journal of Biological Chemistry · Sep 17, 2026Peer-reviewedBiochemistry

FTO separation-of-function mutations alter m6A versus m6Am demethylation selectivity on RNA

Kasun Dilshan Abeyrathne Eluwawalage, Brittany A. Shimanski, Marcin Warmiński, Suma Katta, Rebecca Payne, Yanbao Yu, Joanna Kowalska, Jacek Jemielity, Jeffrey S. Mugridge

This paper reports engineered FTO mutants that selectively demethylate m6A or m6Am RNA modifications, enabling study of their distinct biological roles.

bioRxiv · May 19, 2026 · PreprintBiochemistry