Author

Simon Krost

German Cancer Research CenterORCID 0009-0000-4257-4334Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1

Frequent Co-Authors

Christian Martin SeitziD· 2 shared Anna‐Sophia MastiD· 1 shared Beate KristmanniD· 1 shared Daniel Atar· 1 shared Felix GoerdeleriD· 1 shared Jost LühleiD· 1 shared Oren MoscovitziD· 1 shared Peter H. SeebergeriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

Christian Martin SeitzORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 18, 2026

Pan-B-Lineage Targeting with Adapter CAR-T Cells Controls Antigen-Heterogeneous Lymphoma

Simon Krost, Anna‐Sophia Mast, Daniel Atar…·Christian Martin Seitz

This study shows that using multiple adapter molecules in AdCAR-T cells can effectively target antigen-heterogeneous lymphoma by overcoming antigen-negative relapse.

DOI 10.64898/2026.09.12.751171

humanexperimental assay

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Cancer BiologybioRxivPreprintApr 1, 2025

Cysteine-Engineered CAR-T Cells to Counter Antigen Escape in B Cell Lymphoma

Jost Lühle, Simon Krost, Felix Goerdeler…·Oren Moscovitz

This paper introduces cysteine-engineered CAR-T cells that target both conventional antigens and altered redox states in B cell lymphoma, reducing the risk of antigen escape.

DOI 10.1101/2025.04.01.646520

humanCITE-seq

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