NeurosciencebioRxivPreprint
Nucleus raphe magnus serotonin neurons bidirectionally control spinal nociceptive transmission in mice
Zoé Grivet, Aude Verboven, Franck Aby…·Pascal Fossat
This study shows that NRM serotonergic neurons bidirectionally control spinal nociception through different 5-HT receptors, with 5-HT2c mediating analgesia and 5-HT3 causing hyperalgesia.
DOI 10.1101/2025.04.09.647804