Pascal Fossat

This study characterizes the developmental and functional diversity of Tac1-lineage neurons in the spinal dorsal horn, showing they are polymodal nociceptive in adults.

The paper introduces Spinotrode, a vertebral implant for long-term single-cell recordings in the dorsal horns of behaving mice, revealing new insights into spinal neuron dynamics during natural behaviors.

The paper identifies inhibitory vestibular neurons in Xenopus tadpoles and shows they modulate postural reflexes through interactions with excitatory vestibulospinal neurons.

This study shows that NRM serotonergic neurons bidirectionally control spinal nociception through different 5-HT receptors, with 5-HT2c mediating analgesia and 5-HT3 causing hyperalgesia.

This study shows that C-LTMRs in mice influence social behavior and affective touch, with their dysfunction leading to social isolation and increased excitability promoting pro-social interactions.

The paper identifies a circuit mechanism involving SST+ vlPAG cells projecting to the RVM that regulate analgesia during defensive states in mice.