Rui Geng

This study shows that KDM4 inhibition changes chromatin structure and transcription in embryonic stem cells, with some effects dependent on Setdb1 status.

This study shows that introducing the PWK/PhJ genetic background in HER2/neu-driven breast cancer mice leads to earlier tumor onset, increased immune cell presence, and reduced MHC antigen presentation.

The paper shows that the PWK genetic background alters transcriptional programs, heterochromatin organization, and malignant epithelial state trajectories in NeuT mammary tumors.