NeurosciencebioRxivPreprint
Uncoupling of synaptic loss from amyloid burden by an Alzheimer's disease protective variant of PLCγ2.
Ryan J. Bevan, Emily Maguire, Tom J. Phillips…·Philip R. Taylor
This study identifies a protective PLCG2 variant that preserves synaptic integrity and reduces microglial synapse engulfment in Alzheimer's disease, independent of amyloid burden.
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