Author

Margaret E. Brown

Innovative Genomics InstituteORCID 0009-0000-6355-253XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Christy A GeorgeiD· 1 shared Deirdre A. KillebrewiD· 1 shared Priya Rana· 1 shared Ross C. WilsoniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperCancer Biology

Christy A GeorgeORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintAug 17, 2026

CRISPR-Mediated Targeting of BRAF Oncogenes in Pediatric Low-Grade Glioma

Christy A George, Margaret E. Brown, Priya Rana…·Ross C. Wilson

This study develops and validates CRISPR guide RNAs to target BRAF oncofusions and V600E mutations in pediatric low-grade glioma cells, achieving high indel frequencies and confirming junction excision.

DOI 10.64898/2026.08.12.744431

humanCRISPR screen

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