Author
University of DundeeORCID 0009-0000-6516-3757Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Oliwia N Mruk, Alexandra J. Musk, Sweta Swaminathan…·Ralitsa Radostinova Madsen
This study shows that PIK3CA mutations cause lineage-specific niche changes in vascular endothelium, leading to tissue malformations that can be partially prevented by PI3K inhibition.
Oliwia N Mruk, Ralitsa Radostinova Madsen
This paper presents a method to generate arterial- and venous-like endothelial cells from human iPSCs without PI3K inhibitors, enabling disease modeling of vascular disorders.
Ralitsa Radostinova Madsen, Alix Le Marois, Oliwia N Mruk…·Bart Vanhaesebroeck
The paper uses single-cell analyses to show that oncogenic PIK3CAH1047R reduces IGF1 signaling specificity and enhances EGF responses, leading to increased phenotypic heterogeneity.