Author

Beatrice Bottura

Cancer Research UK Scotland InstituteORCID 0000-0001-7114-4384Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:differential expression· 1 Organism:E. coli· 1 Organism:human· 1 Assay:imaging· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alexa Price‐WhelaniD· 1 shared Alexandra J. MuskiD· 1 shared Ash EanaiD· 1 shared Gail McConnelliD· 1 shared Gwyn W. GouldiD· 1 shared Hannah DaytoniD· 1 shared Jenna N. Brydon· 1 shared Jinyi SuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

Alexa Price‐WhelanORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 28, 2026

Oncogenic PIK3CA mutations cause lineage-selective niche corruption

Oliwia N Mruk, Alexandra J. Musk, Sweta Swaminathan…·Ralitsa Radostinova Madsen

This study shows that PIK3CA mutations cause lineage-specific niche changes in vascular endothelium, leading to tissue malformations that can be partially prevented by PI3K inhibition.

DOI 10.64898/2026.10.26.761693

humanscRNA-seq

𝕏 PostBluesky

MicrobiologyMicrobiologyPeer-reviewedMay 6, 2025

Oxygen Microenvironments in E. coli Biofilm Nutrient Transport Channels: Insights from Complementary Sensing Approaches

Beatrice Bottura, Gail McConnell, Lindsey C. Florek…·Liam M. Rooney

This study quantifies oxygen gradients in E. coli biofilm transport channels using three sensing methods, revealing anoxic conditions that challenge previous assumptions about channel openness.

15 citations

E. coliimaging

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