ImmunologybioRxivPreprint
Microbiome ssRNA as an environmental cue to activate TLR13-dependent tissue-protective programs in CD5Lhi hepatic macrophages
Ryota Sato, Kaiwen Liu, Takuma Shibata…·Kensuke Miyake
The paper shows that microbiome ssRNA activates TLR13 in hepatic macrophages to drive tissue-protective responses, leading to resistance against acute liver injury in Rnaset2-/- mice.
DOI 10.1101/2023.05.11.540294