Author

Emma Barpal

University of California, DavisORCID 0009-0000-7262-0725Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Jennifer N. CashiD· 2 shared Herra G. MendozaiD· 1 shared Lauren K. AndersoniD· 1 shared Matthew Villanueva BragaiD· 1 shared Sheng LiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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2 shared papersBiochemistry

Jennifer N. CashORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 21, 2026

Cryo-EM structure of the sub-50 kD PDZ-RhoGEF catalytic core-RhoA complex reveals an allosteric mechanism for GEF switch

Matthew Villanueva Braga, Emma Barpal, Sheng Li, Jennifer N. Cash

The paper determines the structure of the PDZ-RhoGEF catalytic core-RhoA complex and identifies an allosteric mechanism by which the GEF switch enhances activity.

DOI 10.64898/2026.10.21.760610

experimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintApr 9, 2026

GEF me a break: the consequences of freezing Rho guanine-nucleotide exchange factor catalytic domains

Lauren K. Anderson, Emma Barpal, Herra G. Mendoza, Jennifer N. Cash

This study examines the effects of freezing on RhoGEF protein activity and stability, finding significant variability in activity but preserved thermostability, with no universal cryoprotectant solution.

DOI 10.64898/2026.04.08.717323

protein structureexperimental assay

𝕏 PostBluesky