Author

C. Erik Hack

Utrecht UniversityORCID 0009-0000-7281-8002Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Abhinandan Devaprasad· 1 shared Ana P. LopesiD· 1 shared Aridaman PanditiD· 1 shared Barbara GiovannoneiD· 1 shared Barend O. W. ElenbaasiD· 1 shared Chiara AngiolilliiD· 1 shared Cornelis P. J. BekkeriD· 1 shared Daniëlle KrijgsmaniD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperBioinformatics

Abhinandan Devaprasad

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 27, 2025

Targeting C2 reduces ischemia-reperfusion injury-induced complement activation in preclinical human models

Elisabeth de Zeeuw, Laura M. Tool, Daniëlle Krijgsman…·Linda Gijzen

This study shows that targeting C2 reduces complement activation in human kidney ischemia-reperfusion injury models using 2D and 3D in vitro systems.

DOI 10.1101/2025.10.27.684821

humanexperimental assay

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NeuroscienceJournal of Clinical InvestigationPeer-reviewedMar 14, 2023

Human IAPP is a contributor to painful diabetic peripheral neuropathy

Mohammed M. H. Albariqi, Sabine Versteeg, Elisabeth M. Brakkee…·Niels Eijkelkamp

This study shows that hIAPP aggregation causes peripheral neuropathy in mice and is associated with reduced IENF density and increased hIAPP oligomers in T2DM patients.

10 citations

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BioinformaticsFrontiers in ImmunologyPeer-reviewedSep 17, 2020

CXCL4 links inflammation and fibrosis through transcriptional and epigenetic reprogramming of monocyte-derived cells

Sandra C. Silva‐Cardoso, Weiyang Tao, Chiara Angiolilli…·Aridaman Pandit

This study shows CXCL4 drives inflammation and fibrosis by altering monocyte-derived cell differentiation through transcriptional and epigenetic changes.

56 citations

humanbulk RNA-seq

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