Aridaman Pandit

This study analyzes T-cell receptor repertoires in monozygotic twins with and without Crohn's disease, finding increased TCR overlap in concordant pairs and identifying eight novel TCR clusters potentially linked to the disease.

This study uses scRNA-seq and flow cytometry to analyze immune cell changes in psoriasis patients, revealing altered immune signatures in blood and skin.

The paper identifies a core gene network linked to inflammation and hyper-keratinization in psoriatic skin, associated with disease severity and microbiome composition.

The paper identifies enrichment of SARS-CoV-2 entry factors and interacting genes in peripheral immune cells of healthy and COVID-19 patients.

RegEnrich identifies key gene regulators using a data-driven approach, revealing ETS transcription factors' role in interferon signaling.

This study shows CXCL4 drives inflammation and fibrosis by altering monocyte-derived cell differentiation through transcriptional and epigenetic changes.

The paper identifies top disease-associated cells and genes in IMIDs and proposes drug repurposing targets using a DIME network approach.