Author

Tiffany Chu

Johns Hopkins UniversityORCID 0009-0000-7950-8154Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:clustering· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

Denis WirtziD· 2 shared Pei-Hsun WuiD· 2 shared Aaron Kakazu· 1 shared Carolina CastilloiD· 1 shared Chongguang Jin· 1 shared Eban A. HannaiD· 1 shared Fan WuiD· 1 shared Haitong WangiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCancer Biology

Denis WirtzORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 2, 2026

VITAL-3D: Volumetric Single-Cell Quantification Reveals Microenvironment-Dependent Drug Responses in Breast Cancer

Chongguang Jin, Tiffany Chu, Qiming Zhang…·Pei-Hsun Wu

VITAL-3D quantifies single-cell drug responses in 2D and 3D cultures, revealing microenvironment-dependent efficacy differences in breast cancer.

DOI 10.64898/2026.08.31.748448

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Cell BiologyScience AdvancesPeer-reviewedMar 11, 2026

Accelerated Discovery of Cell Migration Regulators Using Label-Free Deep Learning-Based Automated Tracking

Tiffany Chu, Yeongseo Lim, Yufei Sun…·Pei-Hsun Wu

This paper introduces DeepBIT, a deep learning method for automated cell migration tracking, enabling high-throughput analysis of cancer cell motility under various conditions and identifying new regulators of migration.

DOI 10.1126/sciadv.aea1492

humanspatial transcriptomics

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NeuroscienceNeurobiology of DiseasePeer-reviewedOct 21, 2024

Senolytic therapy preserves blood-brain barrier integrity and promotes microglia homeostasis in a tauopathy model

Minmin Yao, Zhiliang Wei, Jonathan Scharff Nielsen…·Wenzhen Duan

This study shows that senolytic therapy with D+Q preserves BBB integrity and improves cognitive function in a tauopathy mouse model.

35 citationstop 1%

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