Author

Songkuan Zhuang

Shenzhen UniversityORCID 0009-0000-8888-088XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

Jin WangiD· 2 shared Tianshuai Hu· 2 shared Yong XuiD· 2 shared Dayong GuiD· 1 shared Guoping ZhaoiD· 1 shared Hongzhong Zhou· 1 shared Jie LiiD· 1 shared Lei YiniD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Jin WangORCID

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2 papers

Recent·Most cited

Molecular BiologyFrontiers in Bioengineering and BiotechnologyPeer-reviewedMar 25, 2024

CRISPR-HOLMES-based NAD+ detection

Songkuan Zhuang, Tianshuai Hu, Hongzhong Zhou…·Jin Wang

This study develops a CRISPR-Cas12a-based system for rapid and sensitive NAD+ detection using acetylation and CobB reactivation.

22 citations

experimental assay

𝕏 PostBluesky

Molecular BiologyCell DiscoveryPeer-reviewedMay 17, 2022

Reversible regulation of Cas12a activities by AcrVA5-mediated acetylation and CobB-mediated deacetylation

Xiaoman Kang, Lei Yin, Songkuan Zhuang…·Jin Wang

This study shows that Cas12a activity is reversibly regulated by AcrVA5-mediated acetylation and CobB-mediated deacetylation, revealing a secondary safeguard for bacterial CRISPR defense systems.

14 citations

bacteria (other)experimental assay

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