Hepatic Xanthine Oxidoreductase Sustains Antithrombotic Nitric Oxide Signalling Through the Nitrate-Nitrite-Nitric Oxide Pathway
Tipparat Parakaw, Cristina Pérez‐Ternero, Federica Filomena…·Amrita Ahluwalia
This study shows that hepatic xanthine oxidoreductase (XOR) sustains antithrombotic nitric oxide signaling through the nitrate-nitrite-NO pathway, and dietary nitrate can restore this signaling when endothelial NO is deficient.