Author
Wellcome Sanger InstituteORCID 0009-0001-0244-5711Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Thomas Burgold, Emre Karakoç, Emanuel Gonçalves…·Andrew Roger Bassett
The paper introduces a next-generation dual guide CRISPR system for efficient genetic interaction screening, achieving low undesired guide pairs and balanced expression, and demonstrates its application in colorectal cancer cells.
Emanuel Gonçalves, Rebecca C. Poulos, Zhaoxiang Cai…·Roger R. Reddel
The paper presents a pan-cancer proteomic map of 949 cell lines, revealing protein-specific biomarkers of cancer vulnerabilities and showing proteomic data's superior predictive power for drug response.
Emanuel Gonçalves, Aldo Segura‐Cabrera, Clare Pacini…·Mathew J. Garnett
This study integrates drug sensitivity data with CRISPR screens to identify drug mechanisms and biomarkers for cancer therapy.