MicrobiologyPLoS PathogensPeer-reviewed
Epstein-Barr Virus Latent Membrane Protein 1 Subverts IMPDH pathways to drive B-cell oncometabolism
Eric M. Burton, Davide Maestri, Shaowen White…·Benjamin E. Gewurz
This study identifies LMP1-driven metabolic reprogramming in B-cells, showing that IMPDH inhibition sensitizes EBV-transformed cells to apoptosis, suggesting therapeutic targets for LMP1-driven lymphomas.
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