Author

Yiyuan Chen

University of Illinois Urbana-ChampaignORCID 0009-0001-0695-6420Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:yeast· 1

Frequent Co-Authors

Akanksha M. PandeyiD· 2 shared Davinder SinghiD· 2 shared Eric OldfieldiD· 2 shared Ruijie ZhouiD· 2 shared Adi JaiswaliD· 1 shared Annie LeiD· 1 shared Ben MazurekiD· 1 shared Fangrong LiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersMicrobiology

Akanksha M. PandeyORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintAug 11, 2026

SQ109 is a Novel Multitarget Antifungal in Pathogenic Yeasts: Membrane-Active Δ8,14 Sterol Remodeling, Bioenergetic Stress, and Vacuolar Dysfunction

Ruijie Zhou, Akanksha M. Pandey, Davinder Singh…·Eric Oldfield

This paper shows SQ109 targets multiple pathways in pathogenic yeasts, causing sterol accumulation, proton gradient collapse, and vacuolar dysfunction, leading to antifungal synergy and low resistance.

DOI 10.64898/2026.08.10.744041

yeastexperimental assay

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MicrobiologybioRxivPreprintFeb 15, 2025

Activity of Carbazole, Aminoguanidine and Diamine Anti-infectives against Toxoplasma gondii

Davinder Singh, Melissa A. Sleda, Akanksha M. Pandey…·Eric Oldfield

The paper tests carbazole, aminoguanidine, and diamine anti-infectives against Toxoplasma gondii, finding low IC50 values and protonophore uncoupling activity.

1 citation

experimental assayhost-pathogen & immune response

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