Christopher G. Smith

Angiogenic and Immune Predictors of Neoadjuvant Axitinib Response in Renal Cell Carcinoma with Venous Tumour Thrombus

The paper assesses neoadjuvant axitinib response in RCC with VTT using multiparametric analysis and identifies angiogenic and immune predictors of treatment response.

ExoChew: An exonuclease technique to generate single-stranded DNA libraries

ExoChew generates single-stranded DNA libraries by enzymatically converting double-stranded DNA fragments, enabling genome-wide studies of protein-DNA interactions and DNA structures.

Refined characterization of circulating tumor DNA through biological feature integration

This study identifies and integrates three genome-wide features of cfDNA fragmentation to enhance ctDNA detection in ovarian cancer patients.

Integrated clonal analysis reveals circulating tumor DNA in urine and plasma of glioma patients

The paper detects circulating tumor DNA in plasma and urine of glioma patients using sequencing guided by tumor mutations.

Selecting Short DNA Fragments In Plasma Improves Detection Of Circulating Tumour DNA

The paper shows that selecting short DNA fragments in plasma improves the detection of circulating tumour DNA by enriching mutated DNA, enabling identification of copy number alterations previously undetected.