BiochemistryEMBO ReportsPeer-reviewed
DNA binding and lesion recognition by the bacterial interstrand DNA crosslink glycosylase AlkX
Yujuan Cai, Dillon E. Kunkle, Marcel D. Edinbugh…·Brandt F. Eichman
This study identifies key motifs in AlkX critical for ICL repair and shows a genetic variant reduces its activity, increasing bacterial sensitivity to DNA crosslinking.