Author

Michael A. Gapuz

National Laboratory of the RockiesORCID 0009-0001-1931-8188Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Assay:metabolomics· 1

Frequent Co-Authors

Alexander F. Benson· 3 shared Allison Z. WerneriD· 3 shared Gregg T. BeckhamiD· 3 shared Kelsey J. RamireziD· 2 shared Morgan A. IngrahamiD· 2 shared Alissa C. BleemiD· 1 shared Andrea Salazar· 1 shared Andrew J. BorchertiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersSynthetic Biology

Alexander F. Benson

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3 papers

Recent·Most cited

Synthetic BiologyMetabolic EngineeringPeer-reviewedOct 1, 2026

Engineered Pseudomonas putida reconfigures metabolic fluxes to support energy demands during muconate bioproduction from lignin-related aromatics

Rebecca A. Wilkes, Patrick F. Suthers, Andrew J. Borchert…·Allison Z. Werner

This paper investigates how engineered Pseudomonas putida reconfigures metabolic fluxes to enhance muconate production from lignin-related aromatics.

DOI 10.1016/j.ymben.2026.102573

bacteria (other)metabolomics

𝕏 PostBluesky

Synthetic BiologyMetabolic EngineeringPeer-reviewedOct 1, 2026

Expanding the catabolic capacity of Pseudomonas putida to acetovanillone, 5-carboxyvanillate, and vanillyl glyoxylate for muconate production from kraft lignin-derived aromatics

Kathryn M. Mains, Dillon T. Hofsommer, Michael A. Gapuz…·Allison Z. Werner

This paper engineers Pseudomonas putida to catabolize kraft lignin-derived aromatics into muconate, achieving high monomer utilization and carbon conversion efficiency.

DOI 10.1016/j.ymben.2026.102572

experimental assay

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintJul 15, 2026

Overcoming protocatechuate and catechol accumulation in muconic acid production via adaptive laboratory evolution and metabolic engineering in Pseudomonas putida

Alissa C. Bleem, Tracy L. Hodges, Torrey M Lind…·Gregg T. Beckham

This paper improves muconic acid production in Pseudomonas putida by overcoming PCA and catechol accumulation through adaptive evolution and metabolic engineering, showing that increased CatA1 expression enhances pathway efficiency.

DOI 10.64898/2026.07.14.738518

bacteria (other)experimental assay

𝕏 PostBluesky