Author

Kathryn M. Mains

Oak Ridge National LaboratoryORCID 0000-0002-3623-1383Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Alexander F. Benson· 1 shared Allison Z. WerneriD· 1 shared Andrea Salazar· 1 shared Anika J. FriedmaniD· 1 shared Annette Thompson· 1 shared Banumathi SankaraniD· 1 shared Dillon T. HofsommeriD· 1 shared Gregg T. BeckhamiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperSynthetic Biology

Alexander F. Benson

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2 papers

Recent·Most cited

Synthetic BiologyMetabolic EngineeringPeer-reviewedOct 1, 2026

Expanding the catabolic capacity of Pseudomonas putida to acetovanillone, 5-carboxyvanillate, and vanillyl glyoxylate for muconate production from kraft lignin-derived aromatics

Kathryn M. Mains, Dillon T. Hofsommer, Michael A. Gapuz…·Allison Z. Werner

This paper engineers Pseudomonas putida to catabolize kraft lignin-derived aromatics into muconate, achieving high monomer utilization and carbon conversion efficiency.

DOI 10.1016/j.ymben.2026.102572

experimental assay

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BiochemistrybioRxivPreprintFeb 28, 2026

A Hidden Binding Pocket in the β- ketoacyl-ACP Synthase FabB

Ziran Jiang, Anika J. Friedman, Annette Thompson…·Jerome M. Fox

The paper identifies a hidden binding pocket in FabB that allows alternative acyl chain binding, contrasting with FabF's loss of long-chain binding upon mutation.

DOI 10.64898/2026.02.26.708327

E. colistructural biology

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