Author

Spyros Karaiskos

Center for Biologics Evaluation and ResearchORCID 0009-0001-2532-551XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:metabolomics· 1

Frequent Co-Authors

Aadi Gannavaram· 1 shared Aaron ScholliD· 1 shared Bingjie LiiD· 1 shared Binsheng GongiD· 1 shared Joshua XuiD· 1 shared Lance A. LiottaiD· 1 shared Maria Rios· 1 shared Marissa Howard· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Aadi Gannavaram

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2 papers

Recent·Most cited

GenomicsNAR Molecular MedicinePeer-reviewedMar 29, 2025

Zika and Dengue Viruses Differentially Modulate Host mRNA Processing Factors Defining Its Virulence

Aaron Scholl, Binsheng Gong, Bingjie Li…·Sandip De

This study compares the virulence of Zika and Dengue viruses by analyzing host mRNA processing factors and identifies differences in their impact on host cell cytopathic effects.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsbioRxivPreprintOct 11, 2024

Application of Ensemble Machine Learning to Metabolomic Data Identifies Metabolites Associated with Macrophage Polarization

Aadi Gannavaram, Rahul Paul, Spyros Karaiskos…·Padmanabhan Seshaiyer

The paper uses ensemble machine learning on metabolomic data to identify fatty acid metabolites associated with macrophage polarization into anti-tumor M1 or pro-tumor M2 states.

DOI 10.1101/2024.10.11.617846

mousemetabolomics

𝕏 PostBluesky