Ira Horecka

HiMaLAYAS, a Python package, cuts dendrograms, tests clusters for categorical annotation enrichment (hypergeometric, Benjamini-Hochberg FDR), and renders significant annotations beside clustered heatmaps in one workflow.

The paper expands TheCellMap.org to include human genetic interactions from CRISPR-based analysis in HAP1 cells, enabling visualization and exploration of the network.

The paper constructs a genome-scale genetic interaction network from 4 million double mutants in HAP1 cells, revealing conserved genetic network principles across species and uncovering novel gene functions and cancer dependencies.

MassDash provides a web-based tool for visualizing and validating DIA mass spectrometry data across multiple software tools.