Down syndrome postmortem brains exhibit reduction in nifene binding to α4β2* nicotinic acetylcholinergic receptors
Fariha Karim, Nancy Paola Chavez-Jacobo, Christopher Liang…·Jogeshwar Mukherjee
This study evaluates [18F]nifene binding to α4β2* nicotinic acetylcholine receptors in DSAD, AD, and CN brains, finding reduced binding in DSAD compared to AD and CN.