NeurosciencebioRxivPreprint
Dual orexin antagonist DORA-22 suppressed posttraumatic seizures and enhances GABAergic inhibition in dentate granule cells
Sruthi R Konduru, Jesse R. Isaacson, Zihao Zhou…·Rama K. Maganti
This study shows that DORA-22 treatment reduces posttraumatic seizures and restores sleep homeostasis after traumatic brain injury.
DOI 10.1101/2022.04.17.488582