Author

Amanda N. Farrar

Case Western Reserve UniversityORCID 0009-0001-4167-1359Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Anthony R. Allen· 1 shared Drew AdamsiD· 1 shared Elijah H Hayes· 1 shared Marc A Scemama de GiallulyiD· 1 shared Patrick Zhuang· 1 shared Ralston B. GoldfarbiD· 1 shared Yuriy FederoviD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

Anthony R. Allen

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1 paper

Recent·Most cited

Pharmacology & ToxicologyNature CommunicationsPeer-reviewedJul 16, 2025

PRLX-93936 and BMS-214662 are cytotoxic molecular glues that leverage TRIM21 to degrade nucleoporins

Marc A Scemama de Gialluly, Anthony R. Allen, Elijah H Hayes…·Drew Adams

The paper identifies PRLX-93936 and BMS-214662 as molecular glues that use TRIM21 to degrade nucleoporins, leading to cell death and potential therapeutic applications in TRIM21-high cancers.

22 citationstop 2%

experimental assaydrug response / drug discovery

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