Pharmacology & ToxicologyComputational and Structural Biotechnology JournalPeer-reviewed
Exact formula of the total quasi-steady state approximation in competitive target-mediated drug disposition
Taehong Kim, Jaeyun Cha, Hyeseon Jeon…·Jae Kyoung Kim
This paper derives an exact formula for the competitive qTMDD model, improving computational speed and enabling accurate pharmacological parameter estimation in real-world clinical data.