Developmental BiologybioRxivPreprint
OOCYTE AND EMBRYO CULTURE UNDER OIL PROFOUNDLY ALTERS EFFECTIVE CONCENTRATIONS OF SMALL MOLECULE INHIBITORS
Gaudeline Rémillard‐Labrosse, Sydney Cohen, Éliane Boucher…·Greg FitzHarris
The paper shows that oil-covered culture systems reduce the effectiveness of small molecule inhibitors in oocyte and embryo experiments, affecting EC50 values and suggesting potential issues with reproducibility.
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