Author

Melissa A. Hale

Virginia Commonwealth UniversityORCID 0009-0001-5850-3095Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Marina ProvenzanoiD· 3 shared Aileen S. JonesiD· 2 shared Amanda ButleriD· 2 shared Jeanne M. DekdebruniD· 2 shared Julia M. HartmaniD· 2 shared Kameron BatesiD· 2 shared Kiera N. BerggreniD· 2 shared Kobe IkegamiiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMolecular Biology

Marina ProvenzanoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular BiologyNAR Molecular MedicinePeer-reviewedJan 1, 2026

Quercetin selectively reduces expanded repeat RNA levels in models of myotonic dystrophy

Subodh Kumar Mishra, Sawyer M Hicks, Jesus Frias…·J. Andrew Berglund

Quercetin reduces toxic RNA levels and rescues MBNL-dependent mis-splicing in DM1 and DM2 models.

11 citationstop 1%

𝕏 PostBluesky

Molecular BiologyJournal of Clinical InvestigationPeer-reviewedJan 7, 2025

The Splice Index as a prognostic biomarker of strength and function in myotonic dystrophy type 1

Marina Provenzano, Kobe Ikegami, Kameron Bates…·Melissa A. Hale

The paper introduces the Myotonic Dystrophy Splice Index (SI) as a biomarker that correlates with muscle strength and mobility in DM1 patients.

27 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky

GeneticsbioRxivPreprintJul 3, 2024

RNA mis-splicing in children with myotonic dystrophy is associated with physical function

Julia M. Hartman, Kobe Ikegami, Marina Provenzano…·Melissa A. Hale

The paper investigates the relationship between RNA mis-splicing and physical function in children with congenital myotonic dystrophy, finding significant correlations and predictive models.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky