BioengineeringMolecular Therapy — Nucleic AcidsPeer-reviewed
Multiplex Gene Editing Suppresses Random Integration of Hepatitis B Virus DNA in Chronically Infected Liver
Samuel S. Slattery, Wenwen Huo, Amena Arif…·Ryo Takeuchi
This study uses CRISPR-Cas9 to reduce HBV DNA in infected cells, showing it suppresses random integration without affecting chromosomal translocations.