Author

Matthew J. Jansen

Washington University in St. LouisORCID 0009-0001-7110-8743Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Organism:human· 1

Frequent Co-Authors

Elizabeth M. Eultgen· 2 shared Jaiprakash SharmaiD· 2 shared Jonathan D. CooperiD· 2 shared Letitia L. WilliamsiD· 2 shared Marco SardielloiD· 2 shared Mark S. SandsiD· 2 shared Robert O. HeuckerothiD· 2 shared Brian J. DeBoschiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersNeuroscience

Elizabeth M. Eultgen

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2 papers

Recent·Most cited

NeuroscienceActa Neuropathologica CommunicationsPeer-reviewedDec 22, 2025

Enteric nervous system degeneration in human and murine CLN3 disease, is ameliorated by gene therapy in mice

Ewa Ziółkowska, Letitia L. Williams, Matthew J. Jansen…·Jonathan D. Cooper

This paper shows that CLN3 disease causes enteric nervous system degeneration in humans and mice, which can be prevented by neonatal gene therapy in mice.

6 citations

humanmouse

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NeurosciencebioRxivPreprintMay 26, 2023

Bowel dysmotility and enteric neuron degeneration in lysosomal storage disease mice is prevented by gene therapy

Matthew J. Jansen, Letitia L. Williams, Sophie H. Wang…·Jonathan D. Cooper

This paper shows gene therapy prevents bowel motility issues and enteric neuron loss in mouse models of lysosomal storage diseases.

2 citations

mouseexperimental assay

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