Author

Lena Lau

Pfizer (United States)ORCID 0009-0001-8110-4949Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ahu Turkoz· 1 shared Anders MälarstigiD· 1 shared Brad T. Townsley· 1 shared Brian S. EganiD· 1 shared Chames KermiiD· 1 shared Clifford R. Restaino· 1 shared Dörte SchlesingeriD· 1 shared Kristen Jensen-PergakesiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ahu Turkoz

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1 paper

Recent·Most cited

Cancer BiologyeLifePeer-reviewedOct 13, 2025

KDM5 demethylases suppress R-loop-mediated viral mimicry and DNA damage in breast cancer cells

Lena Lau, Kurt Henderson, Ahu Turkoz…·Marie Classon

This study shows that KDM5 demethylases suppress R-loop formation in breast cancer cells, reducing DNA damage and enhancing immune-related gene expression without affecting normal cells.

DOI 10.7554/elife.106249.3

humanDNA methylation

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