Author

Kristen Jensen-Pergakes

Pfizer (United States)ORCID 0000-0001-8622-4352Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Kristen Jensen-Pergakes1 paper · Sanford Burnham Prebys Medical Discovery Institute

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ahu Turkoz· 1 shared Anders MälarstigiD· 1 shared Brad T. Townsley· 1 shared Brian S. EganiD· 1 shared Chames KermiiD· 1 shared Clifford R. Restaino· 1 shared Dörte SchlesingeriD· 1 shared Kurt Henderson· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ahu Turkoz

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1 paper

Recent·Most cited

KDM5 demethylases suppress R-loop-mediated viral mimicry and DNA damage in breast cancer cells

Lena Lau, Kurt Henderson, Ahu Turkoz, Sara B. Linker, Dörte Schlesinger, Brad T. Townsley, Brian S. Egan, Shoba Ragunathan, Robert A. Rollins, Xianju Bi, Zhijian J. Chen, Oleg Brodsky, Clifford R. Restaino, Murali Gururajan, Kristen Jensen-Pergakes, , Marie Classon

This study shows that KDM5 demethylases suppress R-loop formation in breast cancer cells, reducing DNA damage and enhancing immune-related gene expression without affecting normal cells.

eLife · Oct 13, 2025Peer-reviewedCancer Biology