Molecular BiologyThe EMBO JournalPeer-reviewed
Chromatin condensates tune nuclear mechano-sensing in Kabuki Syndrome by constraining cGAS activation
Sarah D’Annunzio, Martina Di Santo, Giulia Vitali…·Alessio Zippo
The paper shows that chromatin condensates, regulated by MLL4, modulate nuclear mechano-sensing and prevent cGAS-STING activation in Kabuki Syndrome.