Author

Pablo Herrero-Alfonso

CIC bioGUNE;ORCID 0009-0001-8891-0206Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein design· 1 Assay:protein structure· 1

Frequent Co-Authors

Alba PejenauteiD· 2 shared Gabriel OrtegaiD· 2 shared Oscar MilletiD· 2 shared Elena Gomez-RubioiD· 1 shared Francesca PeccatiiD· 1 shared Gonzalo Jimenez OsesiD· 1 shared Laura Galvez-LarrosaiD· 1 shared Santos MerinoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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2 shared papersBiophysics

Alba PejenauteORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintNov 9, 2026

Engineering Nanobody Conformational Switches

Alba Pejenaute, Laura Galvez-Larrosa, Pablo Herrero-Alfonso…·Gabriel Ortega

This paper engineers conformational switches using nanobodies that fold upon ligand binding, enabling customizable receptors and sensors for biomarkers and drugs.

DOI 10.64898/2026.11.06.764871

protein structureexperimental assay

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BiophysicsProtein SciencePeer-reviewedMay 15, 2024

Electrostatic Trade-Off between Mesophilic Stability and Adaptation in Halophilic Proteins

Pablo Herrero‐Alfonso, Alba Pejenaute, Óscar Millet, Gabriel Ortega

This study investigates how halophilic proteins achieve stability in high salt environments by analyzing the trade-off between electrostatic interactions and thermodynamic stability.

12 citations

experimental assay

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