Author

Óscar Millet

CIC bioGUNEORCID 0000-0001-8748-4105Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:protein design· 2 Assay:protein structure· 2 Research Focus:cell-cell communication· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alba PejenauteiD· 2 shared Gabriel OrtegaiD· 2 shared Pablo Herrero-AlfonsoiD· 2 shared Carolina MuguruzaiD· 1 shared Elena Gomez-RubioiD· 1 shared Francesca PeccatiiD· 1 shared Ganeko Bernardo‐SeisdedosiD· 1 shared Gonzalo Jimenez OsesiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBiophysics

Alba PejenauteORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BiophysicsbioRxivPreprintNov 9, 2026

Engineering Nanobody Conformational Switches

Alba Pejenaute, Laura Galvez-Larrosa, Pablo Herrero-Alfonso…·Gabriel Ortega

This paper engineers conformational switches using nanobodies that fold upon ligand binding, enabling customizable receptors and sensors for biomarkers and drugs.

DOI 10.64898/2026.11.06.764871

protein structureexperimental assay

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NeurosciencebioRxivPreprintAug 6, 2026

The ALS/FTD-linked protein CHCHD10 associates with the TDP-43 C-terminal domain through a CHCH-helix interface

Karen S. Alarcon-Morales, Sara Pozo, Mauro Aguilera-Toste…·Ganeko Bernardo‐Seisdedos

This study identifies a CHCH-helix interface between CHCHD10 and TDP-43CTD that modulates their assembly equilibria and aggregation behavior.

DOI 10.64898/2026.08.01.742190

humanprotein structure

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BiophysicsProtein SciencePeer-reviewedMay 15, 2024

Electrostatic Trade-Off between Mesophilic Stability and Adaptation in Halophilic Proteins

Pablo Herrero‐Alfonso, Alba Pejenaute, Óscar Millet, Gabriel Ortega

This study investigates how halophilic proteins achieve stability in high salt environments by analyzing the trade-off between electrostatic interactions and thermodynamic stability.

12 citations

experimental assay

𝕏 PostBluesky