SF3B3 / SF3B5 form a metazoan specific transcription module of the U2 snRNP that coordinates Pol II elongation in a splicing independent manner
Dane Vassiliadis, Jesse J. Balic, Olivia Braniff, Andrea Gillespie, William Rothnie, Kelsy Prest, Oliver J. Sinclair, Andrew Das, Ching‐Seng Ang, Mark A. Dawson
The paper identifies SF3B3 and SF3B5 as a transcription module within the U2 snRNP that regulates Pol II elongation independently of splicing.
bioRxiv · Jul 15, 2026 · PreprintMolecular Biology